Is the Severity of Dilated Virchow-Robin Spaces Associated with Cognitive Dysfunction?

نویسندگان

  • Eun Hye Jeong
  • Yong Joo Lee
  • Sang Joon Kim
  • Jae-Hong Lee
چکیده

Virchow-Robin spaces (VRS) are perivascular spaces surrounding the perforating cerebral arteries or arterioles.1,2 They distribute throughout the subarachnoid space to the brain parenchyma. Solutes from the brain parenchyma and lymphatics are drained into VRS, but VRS themselves do not have direct communication with the subarachnoid space.3 Dilated VRS (dVRS) are easily detectable by magnetic resonance imaging (MRI), usually in the basal ganglia (BG) at the level of the anterior commissure and in the deep white matter (WM), along the penetrating vessels.4 They appear as non-enhancing, high T2 and low T1 signals with iso-signal intensities Is the Severity of Dilated Virchow-Robin Spaces Associated with Cognitive Dysfunction?

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Inflammatory proteins and the severity of dilated Virchow-Robin Spaces in the elderly.

Recent studies suggest dilated Virchow-Robin Spaces (dVRS) could be a manifestation of cerebral small-vessel disease, but little is known about their risk factors. As inflammation has been associated with other brain MRI findings, we investigated whether interleukin-6 and C-reactive protein were associated with the severity of dVRS in the eldery. dVRS were assessed in basal ganglia and white ma...

متن کامل

Magnetic resonance imaging features of unusually dilated Virchow-Robin spaces--two case reports.

Two patients presented with unusually dilated Virchow-Robin spaces appearing as cystic lesions of varying size with signal intensity identical to the cerebrospinal fluid on all magnetic resonance pulse sequences. However, fluid-attenuated inversion-recovery (FLAIR) images disclosed small, high intensity foci adjacent to these cystic lesions in one patient. These high intensity foci on FLAIR ima...

متن کامل

Lobar Dementia due to Extreme Widening of Virchow-Robin Spaces in One Hemisphere

Widened perivascular spaces known as Virchow-Robin spaces (VRS) are often seen on MRI and are usually incidental findings. It is unclear if enlarged VRS can be associated with neurological deficits. In this report, we describe a case of lobar dementia associated with unusual VRS widening in one cerebral hemisphere. A 77-year-old woman, seen at a memory clinic, presented with progressive cogniti...

متن کامل

Rating method for dilated Virchow-Robin spaces on magnetic resonance imaging.

BACKGROUND AND PURPOSE Dilated Virchow-Robin spaces are an emerging neuroimaging biomarker, but their assessment on MRI needs standardization. METHODS We developed a rating method for dilated Virchow-Robin spaces in 4 brain regions (centrum semiovale, basal ganglia, hippocampus, and mesencephalon) and tested its reliability in a total of 125 MRI scans from 2 population-based studies. Six inve...

متن کامل

Dilatation of the Virchow-Robin space is a sensitive indicator of cerebral microvascular disease: study in elderly patients with dementia.

BACKGROUND AND PURPOSE Virchow-Robin spaces (VRSs) are CSF spaces that accompany blood vessels as they perforate the brain substance. Dilatation of VRS is associated with microangiopathy. Microvascular disease has a major etiologic and pathogenetic role in dementias. To our knowledge, no investigators have looked at the relationship between dilated VRS on MR imaging and cerebral microvascular d...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015